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Doctor explains why Ozempic use is causing worrying 'Ozempic-sex' side effect

Home> Science> News

Published 14:12 11 Jul 2025 GMT+1

Doctor explains why Ozempic use is causing worrying 'Ozempic-sex' side effect

Performance in the bedroom could be facing a few setbacks

Tom Chapman

Tom Chapman

For those who feel like they're carrying a few extra pounds, the likes of Ozempic, Wegovy, and Mounjaro seem like a godsend.

These semaglutides were originally designed as an anti-diabetic medication, but in 2025, they're proving to be an effective way to tackle obesity.

The problem is, instead of being prescribed the so-called 'skinny jab' by a medical professional, many are turning to online alternatives in the hope of getting that summer body.

Still, with major celebrities ranging from Elon Musk to Sharon Osbourne, Amy Schumer to Tracy Morgan admitting to taking these medications, and with the weight dropping off them, it's no surprise that the general public is scrambling to get similar results.

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It seems these drugs could be affecting your sex lives in a variety of ways (Tara Moore / Getty)
It seems these drugs could be affecting your sex lives in a variety of ways (Tara Moore / Getty)

It's important to weigh up the supposed pros and cons of these jabs, with side effects like 'Ozempic breath' and increased fears of pancreatitis being discussed alongside the potential to reverse liver disease, as well as various cardiovascular benefits.

We've already got a bit raunchy when discussing the supposed 'Ozempic penis' where a gentleman's manhood might appear larger, but on the other end of the spectrum, what about the injections affecting your performance in the bedroom?

After all, what's the point in having the kit if you don't know how to use it?

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Over on Reddit, one Ozempic user was concerned with their lack of sex drive since going on the jab, explaining: "I've been on Ozempic for a few months now and I love it. Almost no side effects and I'm down 30lbs. Halfway to my goal weight. I'm on 1.5mg compounded with Vitamin B.

"The only side effect I have noticed that's causing issues in my life is that I have absolutely no sex drive at all, and I'm almost repulsed by the notion of it. I have more or less the same feelings that I have when presented with a big meal. Like the thought of having sex is almost nauseating.

"If I was single this really wouldn't impact my life very much, but I live with my boyfriend of about 2.5 years, and the sharp decrease in our sex life is causing issues in our relationship. He isn't pressuring me or anything, but we have been kind of growing distant, and we have been bickering."


Others in the thread reported similar 'issues', with one person stating: "Male here 42. Same boat. The new studies show it takes the pleasure out of alcohol and gambling as well. You are not alone. Thankfully I’m divorced and single."

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A third said: "Definitely feel same way and glad I'm not the only one. The drug messes with our hormones so much and I'm thinking about taking some libido pills that will amp up my sex drive."

Still, not everyone was convinced. Someone else went the other way and claimed: "This is not my experience. I (F51) feel like I have an increase in my sex drive. I just don't have an outlet right now. Ugh."

Apparently, there's some genuine science behind it all, with Dr. James Simon, a reproductive endocrinologist, OBGYN and clinical professor at George Washington University, telling The Wall Street Journal: “These drugs do work in the same places that pleasure and sexual interest are located in the human brain—male and female."

As these drugs work by affecting your appetite to make you feel full, it's thought that they may work similarly to the part of our brains that regulates our sex drive.

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With semaglutide users seemingly split on whether they're feeling like they can't bear to be touched, and others tearing a partner's clothes off, it seems this is one potential side effect that's hard to pin down.

Featured Image Credit: Carol Yepes / Getty
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