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Doctor who reversed biological age by 75% in test subjects says major FDA announcement is coming this year

Home> Science> News

Published 15:49 24 Feb 2026 GMT

Doctor who reversed biological age by 75% in test subjects says major FDA announcement is coming this year

The Curious Case of Benjamin Button comes to life

Tom Chapman

Tom Chapman

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As Benjamin Franklin said in 1789, "In this world nothing can be said to be certain, except death and taxes," and as Father Time is a cruel master, he's coming for us all.

Despite the efforts of biohacker Bryan Johnson to reverse aging, most of us are destined to grow old. Even though Johnson claims we'll be able to achieve human immortality by 2039, there are obvious skeptics.

Away from this work, Dr. David Sinclair is also working to 'reverse' the aging process and thinks that we could soon treat our aches and pains as just another medical condition. The professor of genetics at Harvard Medical School’s Blavatnik Institute suggested that humanity is on the cusp of the biggest health transformation since we discovered clean water and vaccines.

We know the world is evolving at breakneck speed thanks to advancements in artificial intelligence, with supporters thinking AI will be used to cure some of the deadliest diseases.

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Sinclair maintains that modern healthcare systems will be 'outdated' in as little as 10 years, all as we move into the realms of reversing aging.

Speaking at the World Government Summit in February 2026, Sinclair led a segment called "The Science of Living Longer and Better". It's said that by the age of 80, over 50% of us have at least five illnesses. This means that eliminating all cancers would only extend the average life expectancy by 2.5 years because of other diseases.

Can we really wind back the clock on aging? (Paramount Pictures)
Can we really wind back the clock on aging? (Paramount Pictures)

Sinclair said that in March 2026, his company will be entering into clinical trials "to test, for the first time in history, whether we can reverse aging and cure diseases."

He thinks this massive leap is because we finally understand aging and how it's not just wear and tear like cars, but to consider our bodies more like computers that can be programmed and reprogrammed.

The idea of 'rebooting' us to become young again is a novel one, with Sinclair adding: "Aging is like scratches on a CD. The DNA is the music. So we get beautiful music when we are young, but when we get old, we cannot read the beautiful music.

“Our cells do not read the DNA correctly, so the cells, they become lost. They become confused, and our old cells do not make the right proteins, and they get diseases.”

Adamant that we can polish the CD, Sinclair wants to get rid of the scratches and "reinstall the software of the body." Sinclair's lab can supposedly reverse the aging of cells, organs, and complex tissues, including the eye and the brain. Boasting some impressive credentials, Sinclair said this can be done by up to 75% in just six weeks.

Results suggest Sinclair and his team were able to cure blindness in animals for the first time, using modified Yamanaka genes to achieve the impressive figures above. The big deal is that the FDA approved the first human trial in age reversal, with Sinclair concluding: "We will know, this year, maybe in the next few months, if age reversal works.”


Looking at the economic implications of slowing aging, Sinclair says that extending a healthy lifestyle by just one year in the USA could generate an extra $38 trillion in economic value due to improved productivity.

At an even higher level, Sinclair noted that declining fertility rates lead to reduced workforce numbers: "There are two solutions, replace them with robots or keep them alive and healthy. Our greatest asset is human productivity.”

While Sinclair and others are sure this is the start of a new era, there are still critics. Replying on Reddit, one person wrote: "They’d have to find a way to either rejuvenate or halt the degradation of telomeres, but even if this goes perfectly, it’ll only keep billionaires around longer."

Another skeptic grumbled: "If it sounds too good to be true, it almost always is."

A third concluded: "For those with limited time left on this earth, they'll take what they can get. But for someone only in their 40's or 50's, worth proceeding with caution on this stuff."

Featured Image Credit: MediaNews Group/Boston Herald via Getty Images / Contributor
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